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Cancer Weekly

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Apoptosis



Research on apoptosis published by scientists at McGill University



March 31st, 2009

According to recent research from Montreal, Canada, "Epidemiological studies suggest that low dietary folate increases risk for intestinal neoplasia. We recently developed a unique tumor model in which mice fed low dietary folate developed DNA damage and intestinal tumors."

"To identify additional mechanisms by which reduced folate intake contributes to tumor formation in this model, we characterized gene expression signatures in tumors. A total of 175 probe sets had altered expression, with the majority (173) showing increased expression compared with normal intestine. Functional categorization revealed that most genes were involved in cancer (51 genes) or cell death...


Source: Cancer Weekly (2009-03-31)

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