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Cancer Weekly

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Bladder Cancer



Data on bladder cancer described by T.X. Lin et al



March 31st, 2009

"We investigated the expression and involvement of miRNA in bladder cancer. An miRNA array was used to examine the differential expression of miRNA in tumor tissues and normal matched controls," scientists writing in the Journal of Urology report.

"The expression of miRNA-143 was confirmed by Northern blot and real-time polymerase chain reaction. The functional role of miRNA-143 in bladder cancer was studied by examining cell proliferation and oncogene expression after miRNA-143 transfection into 2 transitional carcinoma cell lines. miRNA profiling of human bladder cancer and matched normal urothelial epithelium controls revealed that 37 miRNAs were up-regulated...


Source: Cancer Weekly (2009-03-31)

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