Published in Cancer Weekly, March 31st, 2009
"Tg) mice treated with the carcinogen 1,2-dimethylhydrazine developed CEA-overexpressing tumors that resembled human sporadic colorectal cancer. APC1638N/CEA hybrid mice, generated by crossing mice carrying the adenomatous polyposis coli (Apc1638N) gene mutation with CEA. Tg mice, are representative of human familial polyposis and develop polyps...
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