Colon Cancer

Study data from Southern Medical University update knowledge of colon cancer

Published in Cancer Weekly, April 7th, 2009

According to recent research from Guangzhou, People's Republic of China, "Cell migration and invasion are triggered by a number of chemoattractants that stimulate intracellular signaling pathways through regulating reorganization of the actin cytoskeleton. Rac1, an intracellular signal transducer, regulates a variety of cell functions, including the organization of the cytoskeleton, cell migration, and invasion."

"However, currently, very little is known about the roles of Rac1 in the cytoskeleton formation and invasion of human colorectal cancer cells. In our study, Rac1-shRNA was used to silence the Rac1 to reduce its expression specifically in Lovo cells. Our studies...

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Source: Cancer Weekly (2009-04-07)

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