Cancer Weekly
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Life Sciences
Research on life sciences detailed by C. Fonseca and co-authors
April 7th, 2009
"The identification of cancer antigens that contribute to transformation and are linked with immune-mediated tumor destruction is an important goal for immunotherapy. Toward this end, we screened a murine renal cell carcinomac DNA expression library with sera from mice vaccinated with irradiated tumor cells engineered to secrete granulocyte macrophage colony-stimulating factor (GM-CSF)," scientists in the United States report. "Multiple nonmutated, overexpressed proteins that function in tumor cell migration, protein/nucleic acid homeostasis, metabolism, and stress responses were detected. Among these, the most frequently recognized clone was protein disulfide isomerase...
Source: Cancer Weekly (2009-04-07)
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