Published in Cancer Weekly, April 7th, 2009
"Nine genes were significantly deregulated in MMs compared with normal controls. Seven genes were overexpressed. in MMs, including the following: CDKN2C, cdc6, cyclin H, cyclin B1, CDC2, FoxM1, and Chk1, whereas Ube1L and cyclin D2 were underexpressed. Chk1 is a principal mediator of cell-cycle checkpoints in response to genotoxic stress. We...
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