Hepatic Cancer

Researchers at Wuhan University target hepatic cancer

Published in Cancer Weekly, April 7th, 2009

"RNA interference (RNAi) has been successfully applied in suppression of hepatic cancer genes. In hepatocelluar carcinoma cell, one methionine adenosyltransferase ( MAT) isozyme, MATII was found to have two catalytic subunits which were encoded by MAT2A and MAT2 beta respectively," investigators in Wuhan, People's Republic of China report.

"During tumorigeness of hepatocelluar carcinoma, expressions of the two genes were discovered to be increased combining with a switch of MAT ( form MATI to MATII), To figure out the role played by MATII in hepatic cancer, In this study, for the first time we established a dual small interfering RNA ( siRNA) expression system, which...

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Source: Cancer Weekly (2009-04-07)

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