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Cancer Weekly

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Angiogenesis



Research from Stanford University, Medical Department has provided new information about angiogenesis



April 7th, 2009

"Functional recovery after cerebral ischemia is mediated by the regeneration of vascular networks and the restoration of synaptic architecture. Netrins have been implicated in neuronal pathfinding and angiogenesis," scientists writing in the Journal of Cerebral Blood Flow and Metabolism report.

"In this study, we investigated the expression of Netrin-4 and its putative receptors, deleted in colorectal cancer (DCC), Unc5A, and Unc5B after distal middle cerebral artery occlusion in mice. Netrin-4 protein was also administered intracerebroventricularly to examine its effect on angiogenesis and behavioral recovery. Netrin-4 protein was highly upregulated in the...


Source: Cancer Weekly (2009-04-07)

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