Cancer Weekly
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Angiogenesis
Researchers from Adnan Menderes University, Medical Department describe findings in angiogenesis
April 7th, 2009
According to a study from Turkey, "Clear cell renal cell carcinoma (ccRCC) is the most frequently encountered tumor in the adult kidney. Many factors are known to take part in the development and progression of this tumor." "Nuclear factor kappa B (NF-kappa B) is a family of the genes that includes five members acting in events such as inflammation and apoptosis. In this study, the role of NF-kappa B (p50 subunit) in ccRCC and its relation to angiogenesis and apoptosis were investigated. Formalin-fixed and paraffin embedded tissue blocks from 40 patients with ccRCC were studied. Expressions of NF-kappa B (p50), VEGF, EGFR, bc1-2 and p53 were detected...
Source: Cancer Weekly (2009-04-07)
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