Cancer Weekly
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Angiogenesis
Scientists at Albany Medical College, Medical College publish new data on angiogenesis
April 7th, 2009
According to a study from the United States, "Endostatin and anastellin, fragments of collagen type XVIII and fibronectin, respectively, belong to a family of endogenous inhibitors of angiogenesis which inhibit tumor growth and metastasis in a number of mouse models of human cancer. The mechanism of action of these inhibitors is not well understood, but they have great potential usefulness as non-toxic long-term therapy for cancer treatment." "In this study, we compare the anti-angiogenic properties of endostatin and anastellin using cell proliferation and transwell migration assays. Anastellin but not endostatin completely inhibited human dermal microvessel endothelial...
Source: Cancer Weekly (2009-04-07)
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