Myelodysplastic Syndrome

Research from Yamaguchi University in the area of myelodysplastic syndrome described

Published in Cancer Weekly, April 7th, 2009

According to recent research from Yoshida, Japan, "Feline leukemia virus (FeLV) clone33 was obtained from a domestic cat with acute myeloid leukemia (AML). The long terminal repeat (LTR) of this virus, like the LTRs present in FeLV from other cats with AML, differs from the LTRs of other known FeLV in that it has 3 tandem direct 47-bp repeats in the upstream region of the enhancer (URE)."

"Here, we injected cats with FeLV clone33 and found 41% developed myelodysplastic syndromes (MDS) characterized by peripheral blood cytopenias and dysplastic changes in the bone marrow. Some of the cats with MDS eventually developed AML. The bone marrow of the majority of cats with...

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Source: Cancer Weekly (2009-04-07)

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