Pituitary Cancer

Study findings from Medical University of Vienna provide new insights into pituitary cancer

Published in Cancer Weekly, April 7th, 2009

"Currently, no effective alternative treatment exists for progressive, regrowing, nonfunctioning pituitary adenomas (NFPA) that are resistant to conventional multimodality therapy. Temozolomide (TMZ) was proposed as a treatment option for pituitary carcinomas and aggressive pituitary adenomas," scientists in Vienna, Austria report.

"Recently, it was suggested that the responsiveness of pituitary tumors to TMZ depends on the immunoexpression of O-6-methylguanine DNA methyltransferase (MGMT). Therefore, the authors of this report assessed MGMT expression in a series of patients with progressive, regrowing NFPAs to evaluate whether TMZ may serve as alternative treatment...

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Source: Cancer Weekly (2009-04-07)

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