Cancer Weekly
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Bladder Cancer
Reports from Zhejiang University highlight recent research in bladder cancer
April 7th, 2009
"Toll-like receptor 4 (TLR4) was found to be aberrantly expressed in bladder cancer, inducing some genes expression and facilitating tumor progression. Recent data suggest that tumor associated Interleukin-6 (IL-6) correlates with tumor size and grade in bladder cancer," investigators in Hangzhou, People's Republic of China report. "However, the molecule mechanisms of the induction of IL-6 response in bladder cancer cells are not well elucidated. In this study, we manage to find out whether TLR4 signaling is involved in the production of IL-6 by human bladder cancer cells, and the detailed molecule mechanisms by which IL-6 is up-regulated. We selected human bladder...
Source: Cancer Weekly (2009-04-07)
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