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Cancer Weekly

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Breast Cancer



Findings from M. Buijs and co-researchers advance knowledge in breast cancer



April 7th, 2009

In this recent study, researchers in the United States conducted a study "To evaluate the anti-glycolytic effects of 3-BrPA on rats bearing RMT mammary tumors, by determining FDG uptake after intravenous administration of the therapeutic dose. Sixteen rats bearing RMT tumors were treated either with 15 mM 3-BrPA in 2.5 ml of PBS or with 2.5 ml of PBS."

"After treatment, all rats received FDG and were sacrificed 1 h later. 3-BrPA treatment significantly decreased FDG uptake in tumors by 77% (p = 0.002). FDG uptake did not significantly decrease in normal tissues after treatment," wrote M. Buijs and colleagues.

The researchers concluded: "Our study...


Source: Cancer Weekly (2009-04-07)

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