Cancer

New cancer research reported from S. Miccadei and co-authors

Published in Cancer Weekly, April 7th, 2009

"The understanding of cutaneous pigmentation biology is relevant from the biologic and clinical point of view. The binding of alpha-melanocortin and its specific receptor, on the plasma membrane of melanin synthesising cells, plays a crucial role in melanins biosynthesis," researchers in Rome, Italy report.

"Furthermore, loss of MCIR function is associated with an increased incidence of melanoma and non-melanoma skin cancer. The expression of the alpha-melanocortin receptor gene is highly controlled but, at the present, region responsible for tissue-specific activity of the gene promoter has not been identified. We have cloned the genomic sequences upstream the human...

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Source: Cancer Weekly (2009-04-07)

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