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Breast Cancer

Researchers from Fudan University publish new studies and findings in the area of breast cancer

Published in Cancer Weekly, April 14th, 2009

"PALB2 has been recently identified as breast cancer susceptibility gene in western populations. To investigate the contribution of PALB2 mutations to Chinese non-BRCA1/BRCA2 hereditary breast cancer, we screened all coding exons and intron-exon boundaries of PALB2 in 360 Chinese women with early-onset breast cancer or affected relatives from five breast disease clinical centers in China by utilizing PCR-DHPLC and DNA sequencing analysis," scientists writing in the journal Breast Cancer Research and Treatment report.

"Some genetic variants identified in the cases were then studied in 864 normal controls with no personal or family history of breast cancer. Two...

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