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Cancer Weekly

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Cancer Gene Therapy



Iowa State University describes research in cancer gene therapy



April 14th, 2009

Fresh data on cancer gene therapy are presented in the report 'Novel pentablock copolymers for selective gene delivery to cancer cells.' According to recent research from the United States, "In this study, the novel poly(diethylaminoethylmethacrylate) (PDEAEM)/Pluronic F127 pentablock copolymers were found to be able to mediate high-efficiency transfection of human epithelial ovarian carcinoma (SKOV3) cell line while showing significantly lower efficacy in human epithelial retinal (ARPE-19) cell line and Swiss Mouse Fibroblast (3T3) cell line. The intracellular routes of polyplexes were investigated by confocal microscopy after appropriately labeling the polymer and DNA."

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Source: Cancer Weekly (2009-04-14)

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