Cancer Vaccines
Data on cancer vaccines discussed by researchers at Wayne State University
Published in Cancer Weekly, April 14th, 2009
A report, 'Her-2 DNA versus cell vaccine: immunogenicity and anti-tumor activity,' is newly published data in Cancer Immunology, Immunotherapy. According to a study from the United States, "Direct comparison and ranking of vaccine formulations in pre-clinical studies will expedite the identification of cancer vaccines for clinical trials. Two human ErbB-2 (Her-2) vaccines, naked DNA and whole cell vaccine, were tested side-by-side in wild type and Her-2 transgenic mice."
"Both vaccines can induce humoral and cellular immunity to the entire repertoire of Her-2 epitopes. Mice were electro-vaccinated i.m. with a mixture of pGM-CSF and pE2TM, the latter encodes Her-2...
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Source: Cancer Weekly (2009-04-14)
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