Cancer

Study results from University of Heidelberg provide new insights into cancer

Published in Cancer Weekly, April 14th, 2009

According to recent research from Heidelberg, Germany, "The blood vessel-destabilizing Tie2 ligand angiopoietin-2 (Ang-2) acts in concert with the vascular endothelial growth factor/vascular endothelial growth factor receptor system to control vessel assembly during tumor progression. We hypothesized that circulating soluble Ang-2 (sAng-2) may be involved in melanoma progression."

"Serum samples (n = 98) from melanoma patients (American Joint Committee on Cancer stages I-IV), biopsies of corresponding patients, and human melanoma cell lines were analyzed for expression of Ang-2 and S100 beta. Multiple sera of a subcohort of 33 patients were tested during progression...

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Source: Cancer Weekly (2009-04-14)

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