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Glioma Gene Therapy
University of Chicago, Brain Tumor Center details research in glioma gene therapy
April 14th, 2009
Current study results from the report, 'Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo,' have been published. "Conditionally replicative adenoviruses (CRAds) represent a novel treatment strategy for malignant glioma. Recent studies suggest that the cytopathic effect elicited by these vectors is mediated through autophagy, a form of programmed cell death," scientists in the United States report. "Likewise, temozolomide (TMZ), a chemotherapeutic agent used for the treatment of malignant gliomas, also triggers autophagic cell death. In this study, we examined the potential...
Source: Cancer Weekly (2009-04-14)
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