Colon Cancer

Research results from Pennsylvania State University update knowledge of colon cancer

Published in Cancer Weekly, April 14th, 2009

According to recent research from the United States, "Src kinase has been linked to increased motility in the progression and metastasis of human colon cancer, although the mechanisms are not fully understood. Integrins are involved in metastasis by mediating attachment and migration of cells, as well as through transducing signals."

"This study examines the link between Src and integrin activity in the metastatic process in colon cancer cells. To determine Src involvement in integrin expression, the human colon cancer cell line, HCT116, was transfected with an activated Src construct and assayed for its ability to attach to and migrate across collagen and laminin....

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Source: Cancer Weekly (2009-04-14)

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