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Cancer
Palonosetron "Preferred" 5-HT3 Antagonist for Emesis Prevention in Oncology Patients Receiving Highly Emetogenic Chemotherapy
April 14th, 2009
A new release of the NCCN (National Comprehensive Cancer Network) Clinical Practice Guidelines in Oncology on Antiemesis recommends palonosetron as the "preferred" 5-HT3 antagonist in combination with aprepitant and dexamethasone for prevention of emesis in highly emetic risk chemotherapy. Based on the important multicenter study published in The Lancet Oncology by the equipe of Dr. Mitsue Saito, last February (Saito M., Aogi K., Sekine I. et al.; Lancet Oncology 2009 Feb; 10(2):115-24. Epub 2009 Jan 8), the National Comprehensive Cancer Network (NCCN, a not-for-profit alliance of 21 of the world's leading cancer centres), antiemesis panel members have reached consensus...
Source: Cancer Weekly (2009-04-14)
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