Cancer Weekly
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Acinar Cell Cancer
New acinar cell cancer research from S. Larosa et al outlined
April 14th, 2009
"Acinar cell carcinoma (ACC) is a rare pancreatic cancer which may be difficult to distinguish from other solid nonadenocarcinoma tumors. The diagnosis depends on the demonstration of acinar differentiation, obtained with antibodies recognizing various pancreatic enzymes that, although specific, show different sensitivity," scientists writing in the journal Virchows Archiv report. "The C-terminal portion of the BCL10 protein shows homology with carboxyl ester hydrolase (CEH), an enzyme produced by pancreatic acinar cells. We investigated the usefulness of a C-terminal BCL10 monoclonal antibody in the diagnosis of ACCs. We examined normal pancreases and different...
Source: Cancer Weekly (2009-04-14)
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