Published in Cancer Weekly, April 14th, 2009
"We compared the karyotypes from 436 nonselected B-cell precursor ALL patients at initial diagnosis and of 76 patients at first relapse. We noticed a relative increase of karyotypes that did not fall into the classic ALL cytogenetic subgroups (high hyperdiploidy, t(12;21), t(9;22), 11q23, t(1; 19), < 45 chromosomes) in a group of 29 patients at relapse (38%) compared to 130 patients at presentation (30%)....
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