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Hepatocellular Cancer

New findings in hepatocellular cancer described by J.E. Uhm and co-researchers

Published in Cancer Weekly, April 14th, 2009

"We designed a phase II trial of the combination with oxaliplatin and doxorubicin for patients with unresectable HCC to evaluate the overall response rate (ORR) and the toxicity. Forty patients with inoperable, systemic chemotherapy naive HCC were enrolled," scientists writing in the journal Cancer Chemotherapy and Pharmacology report.

"Finally, 32 patients received oxaliplatin (130 mg/m(2)) and doxorubicin (60 mg/m(2)) every 3 weeks. Eighty-two treatment cycles were administered (median 2 cycles, range 1-6). There was no treatment-related mortality. The ORR was 15.6% (95% CI, 3.3-28.7) with five partial responses. The median overall survival and median overall...

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