Hepatocellular Cancer

Recent studies from Drexel University add new data to hepatocellular cancer

Published in Cancer Weekly, April 14th, 2009

"Changes in Winked glycosylation are known to occur during the development of cancer. For example, we have previously reported changes in Winked glycosylation that occur with the development of hepatocellular carcinoma (HCC) and, through the use of glycoproteomics, identified many of those proteins containing altered glycan structures," investigators in the United States report.

"To advance these studies and further explore the glycoproteome, we performed Winked glycan analysis from serum samples depleted of the major acute phase proteins, followed by targeted lectin extraction of those proteins containing changes in glycosylation. Using this method, changes in...

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Source: Cancer Weekly (2009-04-14)

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