Cancer Weekly
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Adenocarcinoma
Study findings from H. Vandekken et al broaden understanding of adenocarcinoma
April 14th, 2009
"Survival rates of adenocarcinomas of the gastroesophageal junction (GEJ) are low, because these tumors are generally in an advanced stage by the time they are detected. Chromosomal regions 1q32, 7q21, and 8p22 display critical alterations in GEJ cancers; however, the genes underlying alterations in these genomic areas are largely unknown," scientists in Netherlands report. "To delineate overexpressed genes, we performed array comparative genomic hybridization (aCGH) and mRNA expression analysis of 15 GEJ adenocarcinoma samples using a fine-tiling cDNA array covering chromosome segments 1q31.3 similar to q41 (193.9-215.8 Mb: 21.9 Mb), 7q11.23 similar to q22.1 (723-103.0...
Source: Cancer Weekly (2009-04-14)
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