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Cancer Weekly

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Angiogenesis



New angiogenesis study findings have been reported by A.D. Norden and colleagues



April 14th, 2009

"Recent clinical trial results suggest that anti-angiogenic therapy may be effective against recurrent malignant glioma. Though these treatments prolong progression-free survival, the extent to which they prolong overall survival is unknown," researchers in the United States report.

"We pooled data from 34 patients treated at a single institution on phase II clinical trials of bevacizumab and cediranib, and we compared these data to 18 patients treated on clinical trials of cytotoxic chemotherapies. In univariate and multivariate analyses, treatment group was a significant predictor of progression-free but not overall survival. Median progression-free survival was 8 vs....


Source: Cancer Weekly (2009-04-14)

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