Myeloma
Research from University Medical Center broadens understanding of myeloma
Published in Cancer Weekly, April 14th, 2009
According to recent research published in the journal Clinical Cancer Research, "Reliable data on the persistence of tumor expression of cancer-testis (CT) antigens over time and consequent analyses of the effect of CT antigen expression on the clinical course of malignancies are crucial for their evaluation as diagnostic markers and immunotherapeutic targets. Applying conventional reverse transcription-PCR, real-time PCR, and Western blot, we did the first longitudinal study of CT antigen expression in multiple myeloma analyzing 330 bone marrow samples from 129 patients for the expression of four CT antigens (MAGE-C1/CT7 MAGE-C2/CT10, MAGE-A3, and SSX-2)."
"CT...
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Source: Cancer Weekly (2009-04-14)
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