Cancer Weekly
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Angiogenesis
Research conducted at Zagazig University has provided new information about angiogenesis
April 14th, 2009
According to a study from Zagazig, Egypt, " Astrogliomas are the most common primary brain tumor. Its progression is the result of activation of oncogenes, inactivation of tumor suppressor genes (TSGs), and expression of various growth factors." "The angiogenesis and p53 in astrogliomas play an important role in its grading, treatment strategies, and hence its clinical outcome. Objectives To analyze the frequency of presentation and the possible co-expression of p53 and angiogenesis marker (CD31) and their clinical implications in astrogliomas. Material and methods This retrograde study included 45 cases with astrocytomas in the form of paraffin blocks. Sections were...
Source: Cancer Weekly (2009-04-14)
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