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Cancer Weekly

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Angiogenesis



University of California details research in angiogenesis



April 14th, 2009

According to recent research from the United States, " Identifying molecular markers for tumor recurrence is critical in successfully selecting patients with stage 11 colon cancer who are more likely to benefit from adjuvant chemotherapy. Interleukin 1 beta (IL1B) and interleukin 1 receptor antagonist (IL1RN) have been shown to play a critical role in the early onset of tumor-associated angiogenesis."

"In this study, we tested whether eight functionally significant polymorphisms within six genes of the angiogenesis pathway [IL1B, IL1RN, vascular endothelial growth factor A (VEGFA), VEGF receptor 2, interleukin-8, cyclooxygenase-2] will predict the risk of tumor...


Source: Cancer Weekly (2009-04-14)

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