Cancer Weekly
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Barrett Esophagus
Study data from University of Arizona update knowledge of barrett esophagus
April 14th, 2009
"Barrett's esophagus (BE) is a metaplastic lesion characterized by replacement of the normal squamous epithelium by columnar intestinal epithelium containing goblet cells. It is speculated that this process is an adaptation to protect cells from components of refluxate, such as gastric acid and bile acids," scientists writing in the American Journal of Gastroenterology report. "In contrast to the normal squamous epithelium, enterocytes of the distal ileum are adapted to transport bile acids from the intestinal lumen. Several bile acid transporters are utilized for effective removal of bile acids, including the apical sodium-dependent bile acid transporter (ASBT),...
Source: Cancer Weekly (2009-04-14)
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