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Vascular Cancer

Research on vascular cancer reported by T. Akiyama et al

Published in Cancer Weekly, April 14th, 2009

"Sphingosine-1-phosphate receptor 1 (S1P(1)) has been shown to play an important role in the migration, proliferation, and survival of endothelial cells. S1P(1) of vascular and lymphatic endothelial cells can be detected by immunostaining of paraffin-embedded sections using a rabbit anti-S1P(1) antibody," researchers in Kurashiki, Japan report.

"In this study, to distinguish vascular tumors from histologic mimics using immunohistochemical means, we evaluated the expression of S1P(1) in a range of vascular tumors. S1P(1) expression was observed in eight of eight hemangiomas, four of four lymphangiomas, four of four epithelioid hemangioendotheliomas, three of three...

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