Cancer Cell Biology
Data from Loma Linda University, Center for Health Disparities Research provide new insights into cancer cell biology
Published in Cancer Weekly, April 14th, 2009
Scientists discuss in 'Extracellular, cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential' new findings in cancer. "The tumor microenvironment is believed to be involved in development, growth, metastasis, and therapy resistance of many cancers. Here we show survivin, a member of the inhibitor of apoptosis protein (IAP) family, implicated in apoptosis inhibition and the regulation of mitosis in cancer cells, exists in a novel extracellular pool in tumor cells," scientists writing in the British Journal of Cancer report.
"Furthermore, we have constructed stable cell lines that provide the extracellular pool with either...
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Source: Cancer Weekly (2009-04-14)
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