Cancer Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Cancer Gene Therapy
Report summarizes cancer gene therapy study findings from S. Rodriguez-Nieto and co-researchers
April 21st, 2009
Fresh data on cancer gene therapy are presented in the report 'BRG1 and LKB1: tales of two tumor suppressor genes on chromosome 19p and lung cancer.' According to a study from Barcelona, Spain, "Losses of heterozygosity (LOH) of the short arm of chromosome 19 are frequent in lung cancer, suggesting that one or more tumor suppressor genes are present in this region. The LKB1 gene, also called STK11, is somatically inactivated through point mutations and large deletions in lung tumors, demonstrating that LKB1 is a target of the LOH of this chromosomal arm." "Data from several independent groups have provided information about the profiles of lung tumors with LKB1...
Source: Cancer Weekly (2009-04-21)
|
