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Cancer Gene Therapy
Research from University of Cologne in cancer gene therapy provides new insights
April 21st, 2009
Fresh data on cancer gene therapy are presented in the report 'Death-associated protein kinase (DAPK) promoter methylation and response to neoadjuvant radiochemotherapy in esophageal cancer.' According to recent research from Cologne, Germany, "Multiple studies have shown that promoter methylation of tumor suppressor genes underlies esophageal carcinogenesis. Hypothetically, methylation resulting in tumor suppressor gene inactivation might result in tumors that are unresponsive to chemotherapy and radiation." "Accordingly, our aim was to investigate if aberrant methylation of the apoptosis-related gene Death-Associated Protein Kinase (DAPK) could be used as a predictor...
Source: Cancer Weekly (2009-04-21)
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