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Cancer Weekly

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Gene Therapy



Researchers from Mount Sinai School of Medicine, Department of Medicine detail findings in gene therapy



April 21st, 2009

A new study, 'AAV for pain: steps towards clinical translation,' is now available. According to a study from the United States, "Recombinant adeno-associated virus (rAAV) vectors consisting of self-complementary genomes and packaged in certain capsids can target primary sensory neurons efficiently and can control neuropathic pain long term by expressing opioid or non-opioid analgesic genes. This review examines the therapeutic potential of the approach in five sections: Pain control in oncology (including a discussion of cancer centers as translational pain research environment); vector biology; safety considerations and immunological lessons learned from rAAV clinical trials of other...


Source: Cancer Weekly (2009-04-21)

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