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Cancer Weekly

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Angiogenesis



Studies conducted at T. Tsuchiya et al on angiogenesis recently published



April 21st, 2009

According to a study from Tokyo, Japan, "Angiogenesis is a critical factor in the progression of solid tumors and metastasis. The aim of this study was to characterise the roles of angiogenic and anti-angiogenic factors on ovarian cancer."

"The expression levels of vascular endothelial growth factor (VEGF, angiogenic factor) and pigment epithelial growth factor (PEDF, anti-angiogenic factor) were measured by real-time polymerase chain reaction and Western blotting in ovarian tumors. Microvessel density (MVD) was evaluated by the total microvessel length in high-power field of tumor tissue preparations. MVD correlated with tumor malignancy. The tissues with the highest...


Source: Cancer Weekly (2009-04-21)

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