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Cancer Weekly

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Cancer Gene Therapy



Data on cancer gene therapy described by investigators at Kyushu University, Research Institute for Diseases of the Chest



April 28th, 2009

Investigators publish new data in the report 'Tetracycline-inducible promoter-based conditionally replicative adenoviruses for the control of viral replication.' "The use of conditionally replicative adenoviruses (CRAds) as a promising strategy for cancer gene therapy has been developed to overcome inefficient transduction of solid tumor masses by replication-deficient adenoviruses. Many modifications have been made to CRAds to enlarge tropism, increase selectivity and lytic ability, and improve safety," scientists in Fukuoka, Japan report.

"However, safety is still a concern in the context of future clinical application of CRAds. Particularly, after injection into the...


Source: Cancer Weekly (2009-04-28)

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