Cancer Weekly
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Cancer Gene Therapy
Researchers from Cell Genesys, Inc. discuss findings in cancer gene therapy
April 28th, 2009
New investigation results, 'Combination therapy with radiation or cisplatin enhances the potency of Ad5/35 chimeric oncolytic adenovirus in a preclinical model of head and neck cancer,' are detailed in a study published in Cancer Gene Therapy. "Ad5/35 chimeric oncolytic viruses (OVs) have earlier been shown to increase the level of vector transduction, intratumoral virus spread and survival in a number of xenograft models when compared with Ad5-based viruses. Because radiation and chemotherapy are the current standards of care for most cancer indications, Ad5/35 OVs have been tested here in combination with either radiation or chemotherapy in a head and neck cancer (HNC) xenograft...
Source: Cancer Weekly (2009-04-28)
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