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Cancer Gene Therapy
Researchers from Pusan National University publish findings in cancer gene therapy
April 28th, 2009
Scientists discuss in 'Expression of HBX, an oncoprotein of hepatitis B virus, blocks reoviral oncolysis of hepatocellular carcinoma cells' new findings in cancer gene therapy. According to recent research from Korea, "Although reovirus has been used in tests as a potential cancer therapeutic agent against a variety of cancer cells, its application to hepatocellular carcinoma cells, in which the hepatitis B virus (HBV) X (HBX) protein of HBV plays a primary role, has not yet been explored. Here, we describe experiments in which we use reovirus to treat Chang liver carcinoma cells expressing either a vector only (Chang-vec) or a vector encoding HBX protein (Chang-HBX)." ...
Source: Cancer Weekly (2009-04-28)
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