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Cancer Weekly

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Gene Therapy



Researchers from INSERM publish findings in gene therapy



April 28th, 2009

Current study results from the report, 'Recurrent genomic aberrations combined with deletions of various tumour suppressor genes may deregulate the G1/S transition in CD4+CD56+ haematodermic neoplasms and contribute to the aggressiveness of the disease,' have been published. According to a study from Rouen, France, "CD4+CD56+ haematodermic neoplasms (HDN) constitute a rare disease characterized by aggressive clinical behaviour and a poor prognosis. Tumour cells from HDN are leukaemic counterparts of plasmacytoid dendritic cells (pDCs)."

"Despite increased knowledge of the ontogenetic origin of these tumours, the genetic causes and oncogenic signalling events involved in...


Source: Cancer Weekly (2009-04-28)

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