Cancer Weekly
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Adenocarcinoma
Researchers at Kanazawa University target adenocarcinoma
April 28th, 2009
According to recent research published in the journal Anticancer Research, "Among the combinations coamplified genes, Myc and ERBB2 or EGFR have attracted much attention for their relevance to cytogenetics, carcinogenesis and cancer therapy. Gene amplification of Myc, ERBB2 and EGFR were examined on 97 formalin-fixed and paraffin-embedded gallbladder carcinomas, by fluorescence in situ hybridization (FISH)." "FISH revealed three tumors had Myc amplification. By dual color FISH, one of these three tumors had two populations of tumor cells with the coexistence of amplified Myc and ERBB2, and Myc and EGFR. The second tumor had a high level of amplification of Myc...
Source: Cancer Weekly (2009-04-28)
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