Cancer Weekly
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Angiotensins
Researchers from Shanghai Jiao Tong University report recent findings in angiotensins
April 28th, 2009
"Angiotensin II (ANG II), the biologically active peptide of the renin-angiotensin system (RAS), is generated by angiotensin-converting enzyme (ACE) and is a regulator of cardiovascular homeostasis. Recently, there has been increasing evidence that ANG II is involved in the regulation of cell proliferation and migration, as well as angiogenesis via the ANG II-type 1 receptor (AT1R)," scientists in Shanghai, People's Republic of China report. "These findings suggest that the ACE-ANG II-AT1R pathway is related to cancer biology. Previous reports have shown that ACE is preferentially expressed in pancreatic ductal adenocarcinoma (PDAC) tissues. Recently a homologue of ACE,...
Source: Cancer Weekly (2009-04-28)
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