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Antivirals
Reports from Yale University, Medical Department add new data to research in antivirals
April 28th, 2009
According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of America, "Autophagy is a highly conserved process that maintains homeostasis by clearing damaged organelles and long-lived proteins. The consequences of deficiency in autophagy manifest in a variety of pathological states including neurodegenerative diseases, inflammatory disorders, and cancer." "Here, we studied the role of autophagy in the homeostatic regulation of innate antiviral defense. Single-stranded RNA viruses are recognized by the members of the RIG-I-like receptors (RLRs) in the cytosol. RLRs signal through IPS-1, resulting in...
Source: Cancer Weekly (2009-04-28)
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