Cancer Weekly
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Astrocytoma
Studies from Hiroshima University describe new findings in astrocytoma
April 28th, 2009
According to recent research from Japan, "The function of the cyclin-dependent kinase (cdk) inhibitor p27 is regulated by translocation between the nucleus (activate) and the cytosol (inactivate). No previous reports have examined the subcellular localization of p27 in glioma which was evaluated here regarding the prognosis in high-grade astrocytomas." "The pattern of subcellular localization of p27 expression was examined immunohistochemically in 49 patients with high-grade astrocytoma who were over 20 years of age. The relationship between p27 localization and the prognosis was statistically examined. Kaplan-Meier survival analysis showed that cytoplasmic p27...
Source: Cancer Weekly (2009-04-28)
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