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Cancer Vaccines
Researchers from Ludwig-Maximilians University, Department of Internal Medicine describe findings in cancer vaccines
May 5th, 2009
Current study results from the report, 'Short-term activation induces multifunctional dendritic cells that generate potent antitumor T-cell responses in vivo,' have been published. "Dendritic cell (DC) vaccines have emerged as a promising strategy to induce antitumoral cytotoxic T cells for the immunotherapy of cancer. The maturation state of DC is of critical importance for the success of vaccination, but the most effective mode of maturation is still a matter of debate," scientists writing in the journal Cancer Immunology, Immunotherapy report. "Whereas immature DC carry the risk of inducing tolerance, extensive stimulation of DC may lead to DC unresponsiveness...
Source: Cancer Weekly (2009-05-05)
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