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Acute Myeloid Leukemia
Study findings from K. Petrie et al provide new insights into acute myeloid leukemia
May 5th, 2009
According to recent research published in the journal Current Opinion in Hematology, "Purpose of review Since the 1970s, the concept of differentiation therapy has been viewed as a promising and revolutionary approach for the treatment of acute myeloid leukemia (AML) and other cancers. However, the successful clinical application of differentiation therapy has only been realized since the late 1980s and only in one subtype of AML, acute promyelocytic leukemia (APL)." "The use of all-trans-retinoic acid (ATRA) and arsenic trioxide, both of which induce degradation of the progressive multifocal leukoencephalopathy/retinoic acid receptor a oncoprotein, in...
Source: Cancer Weekly (2009-05-05)
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