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Recent findings from West Virginia University highlight research in life sciences

Published in Cancer Weekly, May 5th, 2009

According to recent research from the United States, "Fosbretabulin is a novel vascular-disrupting agent that has antitumor activity against anaplastic thyroid cancer (ATC) cell lines, xenografts, and demonstrable efficacy in a phase I trial. This phase II study determined the efficacy and safety of fosbretabulin in patients with advanced ATC and whether fosbretabulin altered the natural history of ATC by virtue of doubling the median survival."

"A secondary aim evaluated the prognostic value of serum soluble intracellular adhesion molecule-1 (sICAM). Twenty-six patients received fosbretabulin 45 mg/m(2) as a 10-minute intravenous infusion on days 1, 8, and 15 of a...

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