Cancer Weekly
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Angiogenesis
Studies from Columbus Children's Hospital yield new data on angiogenesis
May 5th, 2009
According to recent research from the United States, "Clinical trials with antiangiogenic agents have not been able to validate plasma or serum levels of angiogenesis regulators as reliable markers of cancer presence or therapeutic response. We recently reported that platelets contain numerous proteins that regulate angiogenesis." "We now show that accumulation of angiogenesis regulators in platelets of animals bearing malignant tumors exceeds significantly their concentration in plasma or serum, as well as their levels in platelets from non-tumor-bearing animals. This process is selective, as platelets do not take up a proportional amount of other plasma proteins (eg,...
Source: Cancer Weekly (2009-05-05)
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